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Daan Science: Why "Delta" is so aggressive, and whether the new crown nucleic acid rapid test can cope

Author: Site Editor Publish Time: 2020-07-29 Origin: Site

The "Delta" mutant strain was first discovered in India in October 2020. Compared to the original strain of NIV, the "Delta" mutant has 15 mutations, including three key mutations in the stinger protein, which have caused the virus to "Evolution". Current laboratory studies have shown that the mutations in the stinger protein enhance the ability of the new coronavirus to bind to the host cell, making it easier for the virus to enter the cell, which leads to a significant increase in the infectivity and transmission of the "Delta" mutant strain.

"The Delta mutant has three main characteristics.

 

1. stronger transmissibility, shorter incubation period or transmission interval, five or six generations in 10 days, more adaptable to human

 

2. The second is high viral load, high risk of hospitalization, long treatment time and easy development of severe disease in infected patients

 

3. Third, there may be "immune escape", partially avoiding neutralizing antibodies and suppressing the immune response.


Previous "Delta" mutant strains have made several "appearances" in China, including Zhoushan, Zhejiang, Chongqing, Guangzhou, Pingxiang, Guangxi, Shenzhen, Dongguan, and Ruili, Yunnan. The relevant clinical data show that the domestic vaccine still has a protective effect against the "Delta" mutant strain, so the effective means to prevent the "Delta" mutant strain is still vaccination. At the same time, the New Crown Nucleic Acid Rapid Test (NCRT) is the only gold standard for its detection.

 

As an important part of the prevention and control of the new strain of Nucleic Acid, the Nucleic Acid Rapid Test Institute at all levels should pay attention to the ability of the kits used to detect the "Delta" mutant strains, to ensure that the current epidemic mutant strains are covered by the Nucleic Acid Rapid Test, and to avoid off-target omissions.

 

By testing the new crown nucleic acid rapid test reagent of a gene company in Guangzhou, the mutation site of the current new crown virus variant does not fall within the detection target of the new crown nucleic acid rapid test kit, which will not cause off-target detection, and its new crown nucleic acid rapid test kit can ensure the detection of the current popular new crown virus variant.

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