Why is there a high incidence of "re-surgery" of NCCP?
Normally, the human body produces antibodies to protect the body from secondary attacks of the virus after infection. Why do we still get "relapses" of Neoplastic pneumonia? To sum up, there are several reasons.
1, nucleic acid test "false negative"
The nucleic acid test currently used in China is mostly a pharyngeal swab test, which has certain errors. If the operation is not appropriate, not in the deep pharynx fully wipe; or the patient's symptoms are reduced, the pharynx does not have enough virus samples, it will lead to nucleic acid testing "false negative" results.
2, the patient did not establish immunity
There are individual patients who have been discharged from the hospital and are hospitalized again with a positive nucleic acid test. This is because the patient has not developed antibodies of his own, and after discharge, the resistance becomes weaker and the virus proliferates, resulting in a "re-positive" nucleic acid test and the manifestation of symptoms of NCCP.
Among patients with neoconiosis, those with underlying diseases such as diabetes, hypertension and hyperlipidemia, as well as those who are older, are prone to "re-positive" due to their complicated conditions and low immunity.
3. Excessive use of glucocorticoids
Glucocorticoids can suppress inflammatory reactions, improve respiratory symptoms and hypoxemia, inhibit cytokine storms caused by viral infections, and avoid continuous aggravation of lung injury.
However, the massive application of glucocorticoids has the risk of suppressing the immune function of the body, hindering antibody production and making it difficult to completely clear the virus.
4、Re-infection
If the body does not produce antibodies or the immune system is suppressed after infection, secondary infection is likely to occur after re-exposure to the virus.
5、Virus residue
After the production of antibodies, the virus clearance of patients shows individualized characteristics. Some patients may have residual inactive virus in their intestines and feces after recovery. At this time, the nucleic acid test for the new coronavirus will also be positive, but the virus is inactivated and does not have the ability to cause disease and infection.
How to avoid "re-positivity" in patients with Neoplastic pneumonia
Patients who have not established immunity or whose bodies have not been completely cleared of the virus are infectious if they have a positive nucleic acid test. How to avoid the re-surgery of patients with NCCP becomes a key point of work in the treatment of NCCP.
1. Improve the treatment plan
For the first time, the sixth edition of the treatment plan released on February 19 suggested that patients should undergo 14 days of "self-monitoring" after discharge from the hospital and follow up with the hospital during the second and fourth weeks of discharge. In the "New Coronary Pneumonia Treatment Protocol (Trial Version 7)" issued on March 4, the 14-day "isolation management and health status monitoring" was strengthened.
The treatment medication also takes into account the side effects of drugs and the patient's ability to tolerate them, and uses a combination of Chinese and Western medicine to treat patients with Newcastle pneumonia, which helps improve the patient's immunity and promote the formation of their own antibodies.
2. Strict discharge criteria
In Shanghai, based on the discharge criteria stipulated in the "New Coronary Pneumonia Treatment Plan (Trial Version 7)", two new criteria were added for discharging patients who meet the criteria of obvious absorption of exudative lesions in the lungs and negative nucleic acid test on anal swab (stool).
Before the closure of the Fangcai Hospital, Wuhan Jiangan Fangcai Hospital had drawn blood from patients to be discharged with additional viral antibodies
