It has been almost 3 years since the epidemic hit our country, and it has also been 3 years since we went from not knowing much about the New Crown Nucleic Acid Rapid Test to becoming an everyday occurrence. Today we will talk about how the New Crown Nucleic Acid Rapid Test has become convenient step by step?
Let's take a look at the four steps of the NNC rapid test: sampling - sample pre-treatment - nucleic acid extraction and purification - PCR amplification and analysis.
At the end of 2019, the initial outbreak of Neocoronavirus pneumonia, a pneumonia of unknown origin, caused public anxiety. Since this type of pneumonia had not been seen before, its corresponding detection reagents had yet to be developed. The genetic sequence of the virus was then sequenced by "gene sequencing" and published for researchers worldwide to develop detection reagents.
Subsequently, researchers will extract the specific fragments and develop a new rapid test kit with good specificity and high sensitivity based on the principles of gene transcription and PCR amplification. At this stage, we will have to go to the hospital for sampling and rapid nucleic acid testing of the new crown to get the results of the rapid nucleic acid test, and return to the hospital to get the results again after the results of the rapid nucleic acid test of the new crown are available.
In early 2020, due to the development of the New Crown epidemic. Rapid New Crown Nucleic Acid Testing began to spread up and down the country, and several hospitals in the country began to conduct rapid New Crown Nucleic Acid Testing programs. With the further development of the epidemic, the development of "health codes" that can report health information on their own began.
As the epidemic spread throughout the country, the "health code" also developed the color distinction of "yellow code" and "green code", and gradually the "health code" became associated with personal information. The "health code" was gradually associated with personal information, and the results of the rapid nucleic acid test for NSCN were synchronized in real time. On the basis of this, large-scale Nucleic Acid Rapid Test screening was developed accordingly.
Initially, the mass New Coronary Nucleic Acid Rapid Test screening was done in a single person, single test approach. This was accompanied by a shortage of resources for rapid nucleic acid testing. At this point, the "cup handling system" was created to assist the NIC rapid testers with the pre-processing phase of the sample. It can help the testing personnel to complete the work of opening and closing the lid and adding liquid, which greatly improves the efficiency of New Crown's rapid nucleic acid testing. Subsequently, dual-module and dual-cleavage fully automated nucleic acid extractors, highly efficient amplification reagents, and portable amplification instruments were developed to improve nucleic acid purification and enrichment.
With these New Crown Nucleic Acid Rapid Test equipment and New Crown Nucleic Acid Rapid Test reagents, the efficiency of New Crown Nucleic Acid Rapid Test has also been greatly improved. The time for rapid Nucleic Acid testing was also reduced from more than ten hours at the beginning to several hours or even minutes to produce results.
Later, due to the pressure of the epidemic on the NNA rapid test, the large-scale NNA rapid test adopted a multi-combination mode - placing samples collected from multiple individuals in the same sampling tube, and testing samples from 10 people at a time for the NNA rapid test. The initial "5-mix" model has evolved into a "10-mix" and now a "20-mix" model.
Now, the screening mode has changed from pure nucleic acid screening to "antigen screening, nucleic acid diagnosis" mode, further enriching the means of epidemic prevention and control.
In the future, it is believed that with the continuous development of technology, the efficiency and accuracy of the new crown nucleic acid rapid test will be further enhanced. The means of epidemic prevention and control will also be gradually diversified!
