Recently, Zhang Wenhong, director of the Department of Infection at the West China Hospital of Fudan University, said in an interview that the goal of vaccination has shifted and the main goal is to prevent and reduce serious illness.
Vaccine is an autoimmune preparation for the prevention of infectious diseases made from pathogenic microorganisms and their metabolites, artificially attenuated, inactivated or using genetic modification.
It works on the principle that by preemptively injecting into animals the pathogenic bacteria that retain the stimulation of pathogenic bacteria but do not have the power to harm into animals, the immune system in the body produces certain protective substances, such as immune hormones, active physiological substances, special antibodies, etc.;
when animals are exposed to such pathogenic bacteria again, the immune system in the body will, based on the original immune memory, produce a large amount of protective substances to stop pathogenic bacteria The immune system will produce a large amount of protective substances to prevent the pathogenic bacteria from harming the animal based on the original immune memory.
However, vaccination does not mean that you can rest easy. Because all vaccines are not 100% effective, it is not uncommon for people to get sick after receiving a vaccine. This is not because the vaccine is ineffective, but because there is a "breakthrough infection".
What is a "breakthrough infection"? A "breakthrough infection" is when a pathogen breaks through the vaccine's defenses and causes a person who has been vaccinated to contract the disease that the vaccine is supposed to prevent. The lower the effectiveness of the vaccine, the higher the incidence of "breakthrough infection". Even with the most potent vaccines, individual differences can lead to "breakthrough infections" in individuals with lower immune responses.
The researchers found that the delta variant caused more "breakthrough infections" among the statistical cases of "breakthrough infections". The statistics showed that the positive transfer rate for delta in our country dropped to 87.5% among those who received the Coxin vaccine.
The positive conversion rate is the same as the neutralizing antibody conversion rate, meaning how many people developed antibodies after vaccination. Although it is uncertain whether this is due to the reduced protective efficacy of the vaccine against this strain compared to the prototype strain, or whether it is due to the higher infectivity and transmission efficiency of the strain itself. What is clear, however, is that the vaccine is significantly more effective in preventing death and severe disease than it is in preventing mild disease or infection.
Experts suggest that in order to deal with "breakthrough infections", we can accelerate the development of vaccine formulations with higher protection, increase the number of vaccine doses, i.e., booster shots, and adopt new immune boosting technologies.
In addition to the above methods to deal with "breakthrough infection" by enhancing the protection rate, personal protective measures should not be neglected. With the normalization of nucleic acid testing, independent nucleic acid testing is necessary and rapid nucleic acid testing has become an indispensable part of the post-epidemic era.
In order not to interfere with the needs of daily life, the requirements for efficiency of the New Crown Nucleic Acid Rapid Test have been greatly enhanced, and the New Crown Rapid Test has mainly improved the efficiency of amplification.
The use of highly efficient amplification reagents and portable amplification instruments has greatly reduced amplification time and significantly improved amplification efficiency.
