Differences between inactivated and non-inactivated preservation solutions
Virus sampling tubes are used to collect, transport and store samples of influenza, avian influenza, coronavirus and other viruses for subsequent extraction and amplification. After collecting virus samples, it is often not possible to perform PCR testing in a timely manner at the sample collection site again. Therefore, it is necessary to transport the collected virus swab samples. The virus itself can rapidly dissolve into the body regrettably affecting subsequent testing. Therefore, a virus preservation solution needs to be added for storage and transport. For different testing purposes, different virus preservation solutions need to be used. Currently, virus sampling tube manufacturers produce virus sampling tubes mainly divided into inactivated virus sampling tubes and non-inactivated virus sampling tubes and non-inactivated virus sampling tubes. In order to meet different testing requirements and different laboratory conditions for virus testing, it is necessary to use different preservation solutions. So, what is the difference between inactivated and non-inactivated virus tubes preservation solutions?
Preservation solution for inactivated virus sampling tubes: The preservation solution for inactivated virus sampling tubes degrades the sample virus and renders it inactive. It also contains inhibitors to prevent the degradation of viral nucleic acid, which can then be used for subsequent NT-PCR testing. And it can be stored at room temperature for a relatively long time, thus saving the cost of preserving and transporting virus samples.
Preservation solution for non-inactivated virus sampling tubes: The preservation solution for non-inactivated virus sampling tubes maintains the in vitro activity of the virus as well as the integrity of the antigen and nucleic acid, maintains the non-disintegrating viral protein envelope, and maintains the degree of viral sample originality. In addition to nucleic acid extraction and detection, it can be used for virus culture and isolation.
