As the New Crown epidemic has achieved a global pandemic, several countries have invested in the research and development process of rapid nucleic acid testing for New Crown in order to further increase prevention and control efforts and improve prevention and control efficiency.
Recently, a non-invasive breath screening system for neointestinal infection (TestBreathNow), developed by Professor Maosheng Yao of the School of Environmental Science and Engineering at Peking University in collaboration with the Chaoyang District Center for Disease Prevention and Control in Beijing, has been launched in the national "TestBreathNow" program. (TBN) was exhibited at the National "13th Five-Year Plan" Science and Technology Innovation Achievement Exhibition.
It is reported that this method does not require new crown detection reagents, just exhale into the breathing bag for 30s. Most importantly, this method can achieve rapid screening of patients with new crowns in 5-10 minutes, which not only can greatly reduce the time and improve efficiency, but also saves the labor cost consumed by doing the test, and the cost is greatly reduced, with a single test costing only a few dollars.
The principle of this testing technique, as explained by Professor Maosheng, is that the change in the way of energy consumption determines that the chemical composition of the exhaled gas of patients with neo-crown will appear different, and experimental studies have shown that patients infected with neo-crown have significantly lower indicators of propanol levels in the exhaled gas compared to patients with other respiratory diseases.
Currently, this method is still in the clinical trial stage. The rapid nucleic acid test is still the mainstay of neo-coronavirus screening worldwide and is the "gold standard" for diagnosing patients with neo-coronavirus.
What are the differences between the rapid nucleic acid test and the above-mentioned "blow test"?
First of all, the two are different in terms of sample collection. The New Crown Nucleic Acid Test requires professional personnel to conduct the sampling, and to a certain extent may cause vomiting and other uncomfortable symptoms; while the blowing method, the subject can complete the test by themselves, and the whole process is non-invasive, no discomfort.
Secondly, the new crown nucleic acid test requires the transfer of the collected samples, professionals in the negative pressure laboratory to conduct precise and rigorous experiments; while the "breath method" can be done immediately, without the limitations of the experimental equipment.
The new crown nucleic acid test requires the purification and amplification of the collected sample, so that the purity concentration of the sample reaches a certain amount and then uses a very sensitive fluorescent PCR method to make the results very accurate; while the "breath method" mainly focuses on the concentration of a component in the exhaled gas to determine.
However, compared to the conventional Nucleic Acid Rapid Test, the New Crown Nucleic Acid Rapid Test can efficiently increase the detection rate. It is a highly efficient amplification reagent with a portable amplification instrument, which is suitable for one-step extraction, saving extraction time and enabling accurate reporting of results to help prevent and control epidemics!
As the most important prevention and control tool since the epidemic, Nucleic Acid Rapid Test for New Coronas remains the main tool and standard for confirming the diagnosis of patients with New Coronas, and it is still unshakable when the new technology has not passed more clinical trials and has not been supported by a large amount of data.
