Viruses are very tiny organisms, consisting of nucleic acids and protein shells, and do not have their own metabolic machinery or protease system. Therefore, a virus cannot survive if it leaves the host cell. Such a tiny organism can bring us many diseases, such as common epidemic infections usually RNA virus, influenza virus, HIV and influenza A virus. Since it has no cellular structure of its own, the virus itself cannot replicate, but rather invades genes into the host cell and replicates new viruses with the help of the latter's replication system. After a virus sample is collected, the sampled swab is placed in a preservation solution for preservation and transport in order to maintain the activity of the virus sample and prolong the survival time of the virus in the sample.

What is virus preservation solution used for?

Inactivated Virus Preservation Solution inactivates viruses in fresh clinical specimens by denaturing the proteins, eliminating secondary transmission of infection and ensuring the safety of transport and testing personnel. Inactivated samples can be used with a variety of virus extraction kits, nucleic acid extractors for rapid extraction of nucleic acids, and PCR kits for rapid detection of respiratory pathogens, without compromising specificity or sensitivity.

Virus preservation fluid has many functions.

①, easy to operate, the liquid contains components that denature proteins, thus playing a role in virus inactivation;

②, containing inhibitors, greater protection of virus nucleic acid stability from degradation, significantly improve the nucleic acid extraction rate;

③, the product can be stored at room temperature for 12 months before sampling, and the sample can be stored at room temperature for one week after sampling, with good airtightness, which is convenient for preservation and transportation and saves transportation cost.

In addition to the inactivated virus preservation solution introduced above, we also have non-inactivated virus preservation solution. It contains Hank's liquid, potassium chloride, magnesium chloride, calcium chloride, BSA, etc. A variety of antibiotics combined with antibacterial and antifungal effects; bovine serum protein (BSA) as a protein stabilizer, which can form a protective film in the protein shell of the virus, so that it is not easy to decompose and ensure the integrity of the virus; Hank's buffer to build a neutral environment, which helps to increase the survival time of the virus and infection stability. Inactivated and non-inactivated virus preservation solution is usually used for the collection and delivery of virus specimens such as clinical influenza, avian influenza, hand, foot and mouth virus, measles and specimens of mycoplasma, ureaplasma and chlamydia.