Mutated new strains can evade nuclear testing or are linked to the accuracy of the new crown nucleic acid rapid test
A new variant of neocoronavirus was reportedly discovered in a European country in a cluster of aggregated infections with 8 cases carrying the first identified variant of neocoronavirus. These eight patients had typical symptoms of neo-coronavirus infection, but their nasopharyngeal samples were negative for nucleic acid rapid test for neo-coronavirus.
Why did the rapid nucleic acid test for neo-coronavirus fail to screen for new strains? According to epidemiologist Pascal Crepe, this could come from two scenarios: one is that the virus was not detected in the upper respiratory tract, and the second is that a negative NIC rapid test result could mean that the virus has mutated enough to be difficult to detect by the NIC rapid test reagents.
In response to the above, Wuhan University virology professor Yang Zhanqiu said in an interview that the results of the NICR test are related to the stage of disease onset, the NICR test kit and the NICR test method. First of all, the amount of virus in the early stage of the disease is not much, and the NIC rapid test is likely to be negative; in addition, there are differences in different kits from different companies, so it needs to be reviewed at all levels of institutions to achieve accuracy.
In response to reports of negative nucleic acid tests for variant viruses, virologists believe that this situation is closely related to the New Crown Nucleic Acid Rapid Test kits, and that the accuracy and sensitivity of the New Crown Nucleic Acid Rapid Test kits are the key to the accuracy of the New Crown Nucleic Acid Rapid Test results. At present, many domestic companies have launched the New Crown Nucleic Acid Rapid Test products. The New Crown Nucleic Acid Rapid Test Kit produced by Daan Gene is based on fluorescent PCR technology and belongs to the type of double gene detection. It is worth mentioning that Daan Gene nucleic acid detection reagents include UDG enzyme, which can prevent false positives caused by amplification product contamination; and endogenous internal standard can monitor the sampling and PCR amplification process, which can effectively prevent false negative results of New Crown Nucleic Acid Rapid Test caused by abnormal sampling operation or reaction system; negative control and positive control functions, which also effectively prevent false positive or false negative results, New Crown The accuracy of New Crown Nucleic Acid Rapid Test results is effectively guaranteed.
