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What are the roles and differences between inactivated and non-inactivated virus preservation solutions?

Author: Site Editor Publish Time: 2021-02-10 Origin: Site


 

Whether it is nucleic acid testing or virus testing, virus preservation solution and sampling swabs both play a huge role. Sampling swabs are used for the collection of virus samples, while virus preservation solution serves to preserve these virus samples, both to ensure the integrity of the nucleic acid virus and to facilitate the accuracy of later testing. How many types of virus preservation solutions are there?

 

What are the roles and differences?

 

 

There are two types of virus preservation solutions available on the market: inactivated virus preservation solution and non-inactivated virus preservation solution.

 

 

Inactivated virus preservation solution is designed to lyse and inactivate the virus, which can protect the testers from the second infection of the virus. Inactivated virus preservation solution is mainly a modified virus lysis solution for nucleic acid extraction lysate, which has a high concentration of lysis salts to rapidly and efficiently inactivate the virus proteins in the sample to be tested, and also contains RNA enzyme inhibitors, which can protect the virus nucleic acid from degradation and ensure the integrity of the nucleic acid without affecting the subsequent test results. It can also be stored for a relatively long time at room temperature, saving the cost of virus samples and transportation.

 

 

Non-inactivated virus preservation solution is designed to retain the virus protein shell and viral nucleic acid DNA or RNA, so as to ensure the integrity of the nucleic acid in the process of sending the virus samples, although there is a certain risk of infection in case of operational errors, but this preservation solution to maintain the maximum degree of the originality of the virus samples, is a culture-based virus transport medium, it should be noted that a long time preservation The need to maintain strict cryopreservation after sampling.

 

 

Relatively speaking, non-inactivated virus preservation solution for the laboratory requirements will be higher, while the sensitivity is also higher, the application is also more, but it is easier to infect, as long as the sampling and testing operations do not have problems, there will be no risk problems, as for inactivated and non-inactivated virus preservation solution how to choose, this can not be generalized, should be based on different needs to buy, and the price is determined by the high and low The quality of the product is determined by its price.

 

 

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